Biography:

Abstract:

To date  Dioscorea (Yams) in Kenya is a neglected crop, notwithstanding its potential as food and in pharmaceutics as a drug source. Research on neglected crops specifically Dioscorea is a sure way of sensitizing the scientific community and policy makers about it. Several viruses of different genera have been reported to infect yam (Dioscorea spp.). The full diversity of viruses infecting yam, however, remains to be explored.

High-throughput Sequencing (HTS) and use of POX marker methods are progressively being used in the discovery of new plant viral genomes and metabolism processes in plants.

In this study, i will employ HTS on yam to determine whether any undiscovered viruses will be present that would restrict the international distribution of yam germplasm. The finding will work on discovery of a new virus sequence present. Thirty one (31) yam samples will be tested and have tentatively named as virus “yam virus Y” (YVY) .The metabolic reaction which may bring mutation will be tested by use of Peroxidase marker as they achieve the Arabiodisis process in metabolic of the organism. Complete genome sequences of two YVY viral isolates will be assembled and further finding will be done to text five open reading frames (ORFs). ORF1 encodes a large replication-associated protein, ORF2, ORF3 and ORF4 constitute the putative triple gene block proteins, and ORF5 encodes a putative coat protein as yam  contain dioscorin which is full of protein. Considering the species demarcation criteria of the family Betaflexiviridae, YVY should be considered as a novel virus species in the family Betaflexiviridae. Further finding work will be needed to understand the association of this new virus with any symptoms and yield loss and its implication on virus-free seed yam production.

Biography:

Abstract:

Recently India has undergone rapid urbanization and industrialization resulting into remarkable changes in the life style of Indian People. Most Urban People lead sedentary life, consume oral tobacco, adopt Smoking habits eat rich fat diet or, Junk food. So, ultimately India became the diabetic Capital of the world . The Treatment of diabetes ruins many family of urban and ruler Indians. Therapeutic Potential of wheat grass (Triticum aestivum) is Known but not popular. In the Present Investigation an effort has been made to assess the anti diabetic properties of wheat grass in experimental rats. Administration of Wheat fresh grass (2-6 g/day) for 90 days, Significant blood glucose lowering effect in experimental alloxan induced diabetic rats.

So this research appears to be great importance in evolving in cheap treatment for diabetics. Much More details on these will discussed during Presentation.

Biography:

Abstract:

The objective of the Research paper is to identify the treatment of Scabies in homeopathic.  The research Project is experimental and descriptive. The population in the research is the patients of scabies. The researcher selected twenty patients of scabies in Tehsil  Kabal of district Swat as a sample.  The sample was kept under controlled observation. Primary and secondary data was collected about the scabies and its treatment. Different medicines were prescribed to a group of the sample consisting of 10 patients. The second group consisting of 10 patients of the sample was prescribed the mixture of PUMMARIA INDICA and AJUGA BRACTEOSA  Both the groups were interviewed and observed by the researcher. The research finds out that the mixture of PUMMARIA INDICA and AJUGA BRACTEOSA is more effective treatment of scabies than the treatment prescribed by the previous research works.

Biography:

Abstract:

This study evaluated the anti-inflammatory and diuretic activities of ethanol dried fruit extracts of Xylopia aethiopica using adult wistar albino rats as experimental model. Experiment was conducted in a Completely Randomized Design (CRD). Eighteen rats irrespective of gender were used for the study of anti-inflammatory activity and the rats were divided into six groups of three rats each. Data were analyzed using special package for social scientist (SPSS) version 20.0 and subjected to analysis of variance (ANOVA), means separation was done by Ducan multiple range test (DMRT) at 5% level of significance. The anti-inflammatory effect was evaluated on egg albumen-induced paw oedema in albino rats. A positive control containing 200mg of Aspirin and a negative control containing normal saline was used. The negative control showed a high inflammation within the time intervals while the positive control showed a low inflammation. The extract of the fruit exhibited anti-inflammatory property at different time levels that was dose dependent. The average inflammation decreased as time intervals increased (5.83 ± 0.29 to 4.00 ± 0.00 mm). The percentage inflammation increased as interval decreased (86.40 ± 4.96 to 91.53 mm) and the highest inhibition was seen in the extract of the highest concentration (4.54 ± 12.10 mm) for 500mg. A significant difference (p<0.05) exists among the dose levels. The diuretic effect was evaluated using twenty-one adult rats of seven groups of three rats each. Ethanol fruit extract of the plant was administered intra-peritoneally to the rats at doses of 500, 250, 125, 62.25 and 31.5mg/kg body weight respectively. Furosemide (40mg/kg) was used as positive control. The diuretic effect was evaluated by measuring the urine volume and urinary electrolyte excretion. The extract produced a significant increase in urine volume at 500 and 250mg/kg (4.67 ± 0.12 ml and 3.27 ± 0.25 ml) respectively and enhanced urinary excretion of sodium, chloride and potassium significantly (P< 0.05) but had no significant effect on bicarbonate (p>0.05). Findings of this study revealed that ethanol dried fruit extract of Xylopia aethiopica has potential as anti-inflammation and diuretic properties.

Biography:

Getahun Tadesse Gurmessa was born in west Oromia, Ethiopia, in 1983. He received his B. Ed. (in chemistry) and M. Sc. (Organic Chemistry) degrees from Jimma University, in 2008 and 2011, respectively. After working at position of lecturer at Jimma University chemistry department from July 2011 to August 2014, he enrolled for his PhD degree at University of Botswana chemistry department. He has completed his PhD in 2018 under the direct supervision of Prof. R.R. T. Majinda.   His PhD research work was on isolation of plant metabolites with biological importance. He has published his papers in peer-reviewed journals. His main areas of research interest are Natural product chemistry and organic synthesis. He is a member of Ethiopian chemical society and Oromo society of sciences and technology. Currently Dr. Getahun Gurmessa is working as Assistant professor of organic chemistry at chemistry Department Wollege University, Ethiopia.

Abstract:

Erythrian brucei is a tree grown only in Ethiopia. It grows up to the eight of 15-20 m long with colorful flowers. In different parts of the country the root and stem bark of this plant is used to treat ear infection and other diseases. Previous studies revealed that the flower and seed of E.brucei contain biologically active alkaloids; however, there was no report for the non-alkaloidal constituents of this plant. Recently, however, we did a comprehensive phytochemical investigation on root bark, stem bark and twigs of the plant concentrated on nonalkaloidal compounds. In the study we isolated biologically significant compounds and come up with new compounds which were not isolated so far from the nature and different co-metabolites. The identities of the compounds were established based on spectrometric and spectroscopic analysis including MS, 1D and 2D NMR. Resazurin based antibacterial minimum inhibitor concentration (MIC) and DPPH antioxidant assay were carried out on some selected compounds using standard references chlorophenicol and trolox respectively. The tested compounds showed promising antibacterial activity up to (IC₅₀ = 0.0625 mg/mL) and antioxidant activity (IC₅₀ = 1.1μg/mL) comparable to standard references. The structures of the newly reported compounds and other co-metabolites were presented in Fig 1.

Biography:

Emmanuellah Lekete-Lawson (Mrs.) is a Microbiologist/Plant Pathologist. She is a PhD candidate. Her research interest includes: An integrative study to identify metabolic alterations and Mechanical Forces Exerted By Fungal Pathogens on Host Tissues, Characterization and management of thread blight disease on Cocoa, New disease reports on Oil palm and coconut and management. She has published a number of Scientific papers in several scientific journals and has presented more than 40 papers at both local and international conferences and workshops. She is the head of Plant Health Unit of Council for Scientific and Industrial Research (CSIR)-OPRI and a reviewer to quite a number of reputable scientific journals. 

Abstract:

Biography:

Onunekwu Charles has completed his MSc at the age of 27 years from Michael Okpara University of Agriculture Umudike Nigeria. He is currently teaching at Resonance Model Secondary School Umuahia Nigeria

Abstract:

Many young men, women and even the elderly are addicted to Cannabis intake abuse despite its predictable toxicological consequences. In this paper we studied the toxic effects of oral administration of methanol extract of cannabis sativa seeds using total of forty male Wistar Rats. Animals randomized were into five groups (n=8rats) of approximately equal weight. Group 1 received 100mg/kg of the of the extract, group 2 received 200mg/kg of the extract, group 3 received 300mg/kg dosage of the extract, group 4 received 2ml of olive oil and group 5 received distilled water for 14 days. Result for AST was significantly (p<0.05) higher in groups 2 (57.00±13.00IU/L) and 3 (59.33±10.53IU/L), compared with normal control group 5 (31.33±1.53 IU/L). Significantly (p<0.05) higher serum ALT was observed in groups 2 (50.00±12.52IU/L) and 3 (56.33±10.21IU/L). Results for kidney function, shows significantly (p<0.05) higher serum urea concentration in group 3 (13.75±2.41mg/dl) compared with the control group (8.75±1.60mg/dl). Serum creatinine concentration was significantly (p<0.05) higher in group 2 (2.25±1.18mg/kg) and group 3 (2.38±1.57mg/kg) when compared with the control group (1.09±0.13mg/kg). Significantly (p<0.05) higher SOD values was obtained in group 3 (72.64±5.90mg/kg) when compared with normal control group (19.62±4.26mg/kg). In conclusion, the study showed that oral-administration of Cannabis sativa caused a dose dependent hepato-renal toxicity.

Many young men, women and even the elderly are addicted to Cannabis intake abuse despite its predictable toxicological consequences. In this paper we studied the toxic effects of oral administration of methanol extract of cannabis sativa seeds using total of forty male Wistar Rats. Animals randomized were into five groups (n=8rats) of approximately equal weight. Group 1 received 100mg/kg of the of the extract, group 2 received 200mg/kg of the extract, group 3 received 300mg/kg dosage of the extract, group 4 received 2ml of olive oil and group 5 received distilled water for 14 days. Result for AST was significantly (p<0.05) higher in groups 2 (57.00±13.00IU/L) and 3 (59.33±10.53IU/L), compared with normal control group 5 (31.33±1.53 IU/L). Significantly (p<0.05) higher serum ALT was observed in groups 2 (50.00±12.52IU/L) and 3 (56.33±10.21IU/L). Results for kidney function, shows significantly (p<0.05) higher serum urea concentration in group 3 (13.75±2.41mg/dl) compared with the control group (8.75±1.60mg/dl). Serum creatinine concentration was significantly (p<0.05) higher in group 2 (2.25±1.18mg/kg) and group 3 (2.38±1.57mg/kg) when compared with the control group (1.09±0.13mg/kg). Significantly (p<0.05) higher SOD values was obtained in group 3 (72.64±5.90mg/kg) when compared with normal control group (19.62±4.26mg/kg). In conclusion, the study showed that oral-administration of Cannabis sativa caused a dose dependent hepato-renal toxicity.